I used the .338 win for a long time with great results for moose mainly but also took deer and bears with it. I have now sold that rifle and now use a 7mm rem mag and quite frankly don't miss the bigger one a bit. I also have used it on game from pronghorn to moose and everything drops as fast as a .338 shot does. If you are hunting areas that could offer a long shot then the big 7 has a slight advantage over an 06. If your shots never go past 300 yds then flip a coin they all shoot flat enough.