On a few occasions when I have gone up to nose-bleed levels I have missed deer.
trouble with climbing to high is that the kill zone appears smaller. it does take much of a shakey pin to miss the kill zone.
if you bend at the waist on flat terrain the pin would be the same as on the ground. on hilly terrain things change. severe down hills shoot shorter than they are for me. if I got a target at 40 yards down a severe hill it will shoot more like 32 to 33 yards instead of the 40...