Minute of pie plate is great, as long as the deer doesn't move, or you don't hit a limb, etc. Then your shot at the edge of the pie plate could become a gut shot or worse.

I want my arrow to hit where my pin is in a hunting situation. Practice until you are as accurate as possible at a given distance, then limit your shots to that distance and below.

I had a one pin set up that allowed me a 6" kill zone, 3" up and 3" down, out to about 35 yards. I've since gone to a pendulum, as it will put my arrow where the pin is, shrinking my kill zone and increasing my margin for arrow should a variable change. See the spot, hit the spot, is what I strive for.