When you guys are picking calibers suitable for hunting pronghorn, I think that some of you are using a little too much gun. I wouldn't imagine buying a 300 magnum for pronghorn and a few coyotes. I would think that something in the measure of a .243 - .270 would be ideal. If you really feel the need to move into the magnum caliber I would go no larger than the 7mm magnum. In fact, that might be the ideal choice due to the wide variety of bullets available in 7mm.