The Latest Word on EIC
09-13-2007, 08:05 AM
#1
Nontypical Buck
Thread Starter
Join Date: Feb 2003
Location: Colville WA USA
Posts: 1,974
The Latest Word on EIC
Here's the latest word about the EIC Test
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Hi, it's Katie from of the U of MN.
Yes, we have been travelling around the area collecting samples for our EIC study. We've been collecting samples to obtain an unbiased (as far as EIC affected) sampling of the Field Trial labradors to determine how common carriers are within the population.
We do believe that we have found the mutation responsible for EIC. This is not verified through functional studies (future research), and it has not yet been peer reviewed, as we are in the midst of writing the manuscript. This test is not considered a certified result at this point. Given this, we are confident in our test's ability to provide a VERY high likeliness of status.
We will NOT ever disclose results for any dog to the public in any way. We will NOT be the keepers of any public database for test results. This would be something setup either as a breed club moderated forum, or may be done if/when the test is contracted out (similar to CNM). We depend on breeders/owners to provide us with samples, and confidentiality is an important factor in people's decision to participate.
Further samples are only being accepted on a case by case basis at this time.
Thanks to all who have helped us get this far!
Katie Minor
.
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Hi, it's Katie from of the U of MN.
Yes, we have been travelling around the area collecting samples for our EIC study. We've been collecting samples to obtain an unbiased (as far as EIC affected) sampling of the Field Trial labradors to determine how common carriers are within the population.
We do believe that we have found the mutation responsible for EIC. This is not verified through functional studies (future research), and it has not yet been peer reviewed, as we are in the midst of writing the manuscript. This test is not considered a certified result at this point. Given this, we are confident in our test's ability to provide a VERY high likeliness of status.
We will NOT ever disclose results for any dog to the public in any way. We will NOT be the keepers of any public database for test results. This would be something setup either as a breed club moderated forum, or may be done if/when the test is contracted out (similar to CNM). We depend on breeders/owners to provide us with samples, and confidentiality is an important factor in people's decision to participate.
Further samples are only being accepted on a case by case basis at this time.
Thanks to all who have helped us get this far!
Katie Minor
.
09-13-2007, 08:24 AM
#2
Nontypical Buck
Thread Starter
Join Date: Feb 2003
Location: Colville WA USA
Posts: 1,974
RE: The Latest Word on EIC
Here's some more
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Katie Minor was at the club today and is supposed to be back on Sat, but she said she had almost every dog in the trial sampled so she might head back home early.
I was able to talk more in depth with her about the progress in the research.
The news is good. The test is here, it is reliable and the patent is pending. The only thing left before the test is brought to market is resolving a few legal issues, which is partially what this batch of samples is for. They need a larger sample size to validate the test.
The good news is the test is very reliable. The P-values were excellent and all the other statistical data are very good.
This is a reliabe test and might be available by Novemeber.
The owners of dogs sampled at recent trials such as this one will recieve a result on the EIC status of their dog. The MOI is Autosomal rec. as previously belived. The U of M is planning on maintaining a verifiable database similar to that for CNM, but they may pass that off to another group such as OFA or similar.
This research is not focused on a cure, but there is some interest from other groups who may take up that mission.
So, there is good news just ahead for those of us who are concerned with EIC. We will have a test that will allow us to breed knowing we are not going to produce EIC affected pups. It doesnt help those who currently have affected dogs, but it is good to know that the next one can be clear.
~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~
Katie Minor was at the club today and is supposed to be back on Sat, but she said she had almost every dog in the trial sampled so she might head back home early.
I was able to talk more in depth with her about the progress in the research.
The news is good. The test is here, it is reliable and the patent is pending. The only thing left before the test is brought to market is resolving a few legal issues, which is partially what this batch of samples is for. They need a larger sample size to validate the test.
The good news is the test is very reliable. The P-values were excellent and all the other statistical data are very good.
This is a reliabe test and might be available by Novemeber.
The owners of dogs sampled at recent trials such as this one will recieve a result on the EIC status of their dog. The MOI is Autosomal rec. as previously belived. The U of M is planning on maintaining a verifiable database similar to that for CNM, but they may pass that off to another group such as OFA or similar.
This research is not focused on a cure, but there is some interest from other groups who may take up that mission.
So, there is good news just ahead for those of us who are concerned with EIC. We will have a test that will allow us to breed knowing we are not going to produce EIC affected pups. It doesnt help those who currently have affected dogs, but it is good to know that the next one can be clear.
