I was going to buy me a 223 for my new yote adventures in sw Florida. But I did some research and found that Winchester makes a 110 grain 3006 bullet.

WATCH OUT I can use my 06 weatherby topped with my kahles 3.5 - 10 x 50mm deadly and gives you the ability to hunt late very very late or early very very early.

100 or 110grn bullets out of a .30-06 SEEM like a great idea in theory, but in application, they fall short. The ballistic coefficients of these stubby little 30cals are terrible, and they have to be loaded VERY conservatively otherwise they'll be over-spun (I had Speer 100grn "Plinkers" that looked like buckshot patterns at 10ft. MV of 3550fps).

I HAVE used 125grn Speer TNT's in a .30-06 (10yrs ago) for prairie dogs. I was right around 3100fps, and they were frankly too light for long range work, but they WERE a little nicer on coyote pelts than 150grn bullets.

Personally, after using several different "light for caliber/cartridge" bullets for coyotes over the last 20yrs, if I'm going to run a .30-06, I'm just going to use 150's either in a highly frangible design, or a fairly HARD design, and leave the lightweights alone. Why shoot a 30cal if you're just going to take the long range capabilities away? Pelt damage with a 150grn A-Max or SST running 2850fps was less for me than a 125grn TNT running 3200fps, and my down range trajectory is MUCH better with the heavier bullet.

Didn't someone offer a 50gr bullet/sabot round for the 30-06?If I remember right it was ultra fast.Right up there with the swift if not faster.

I'm guessing you're refering to the Remington "Accelerators". I haven't seen them in years, but they were a much better idea in theory than they were in practice. If you pushed them "ultra fast", say .220 swift speeds, they were way over-spun (3800fps from a 1:10" twist is no bueno). The recommended load data was in the 3000-3300fps range.

The biggest issue was they were terribly inaccurate. The sabot weighed enough that it effected the bullet pretty severely when it detached. In two rifles I tried them in (a Ruger .30-06 and a custom Mauser .308win springfield dual groove that I built) gave TERRIBLE accuracy. These were rifles that were sub-MOA with 150 and 165grn bullets, but the best I could group with the accelerators was in the "minute of PALM" range at 100yrds.

It's too simple to make it this complicated. If all you have is a .30-06 and you want to hunt coyotes, pick a bullet profile and weight that your rifle likes, then make sure you're either using a hard enough bullet to prevent expansion (limit energy transfer), or using a frangible bullet at a range where it won't exit (over 50yrds, again, limiting energy transfer). Same rule applies for .243win, .308, .300wm, whatever...

Just adding my .02, we here in Southampton Virginia can only use rimfire day or night and shotgun. I carry a shotgun and my son has a .17HMR. Only killed foxes so far and have not had any trouble but I know the yotes are tougher. We hopefully will have more input later as we try again.