what is the best combo for wood chuck in a 308 casing?

A little more info please.
Are you shooting this round out of a sling shot or bolt or lever or contender or what?

Wtex

bolt, remington model 700

I'd try the Hornady 110 V-Max at about 3300'/sec.

leffler,

Your Remington has a 1-10" twist bore. Usually, this twist is a little fast for bullets that weigh less than 125-130 grains. If your set about using the lighter bullets, the only way to find out how your rifle shoots them, is to try them. Some years back I had pretty good results in my .308 W. Good luck.

Us a 168 grain Hornady BTHP or A-max.