How do you true up the sites on a Ruger Vaquero? They are not adjustable & the gun shoots to the left.

Unless you want to file out the rear sight notch or alter the front sight, there is not much you can do except to compensate by changing your aiming point. Sometime you can try different loads and find one that hits closer to the POA. Thats the only thing I don't like about the Vaquero. You could go with a scope or red dot but that wouldn't be a cheap fix.

Depending on how far to the left it shoots the factory will turn your barrel

First be sure it's the gun and not the shooter.

That would make a great pistol target, lol.