What load would you guys recommend to shoot out of a TC ProHunter XT .50 cal, Nikon Omega BDC scope?

250Gr Bonded Shock Wave for hunting 250 gr Regular Shock Wave for pratice.
Use Blackhorn powder 115,120 ,or 125 gr should give a good group, should try them all use load that gives best group.

Is the bonded and regular going to fly the same?

Anybody else wanna help out?

They will fly the same, the bonded are better, for a hunting load. So most say but, I have never had an issue with with the non bonded and terminal effect on deer.

I have a standard recommendation for any .50 inline. Either a 250 grain or 300 grain .452 Speer Deep Curl in the Harvester short black sabot (H5045SB) over whatever powder charge shoots best in your gun. One of my inslines seem to favor the 300 grainers and the other one the 250s. Either way, any deer within 200 yards is dead.