Anyone ever done it? What charge did you use? Where can you hunt these? Sounds like fun to me. I would like to do it someday.

There is big ranch not too far from here called Thunder Hills. They have trophy buffalo hunts, and some folks do it with blackpowder as well as archery. I have heard that arrows and big conicals are very effective on this big beasts, and high velocity CF rifles like the 7 Rem Mag are not. You might do a search on Thunder Hills Buffalo Ranch, or something similar - don't remember for sure - but they have a website with a lot of info.