From my experience, the only bullets I wouldn't use for whitetails with your .300 are Nosler Partitions. I do love Noslers in my .300, just not for deer. I use them all the time for elk, as the bullets hold together and penetrate very well on such a large animal. However, with whitetails, the noslers don't mushroom soon enough and end up "piercing" the deer like an arrow, rather than mushrooming and making the deer's body absorb the full impact of the bullet. As a result, and I have tried hunting whitetails with my noslers after my elk hunts were over, I've lost several deer hit with noslers that would have easily gone down had they been hit with something with a softer point.