ORIGINAL: Matt / PA

There is absolutley no standard for this........really.
Even the same animal at the same yardage standing in the same spot can make for 2 very potentially different outcomes.......is the animal alert?, relaxed?, bedded? Exactly broadside? etc etc. A bedded animal at 35 yards can be a much easier shot than a wired one at 20 and so on.
Also individual skills and type of game your after changes this quite a bit.......A moose standing broadside at 40 yards is a very different shot than a deer in the same position.

The situation, animal position, size, lighting and everything else I can think of can make a shot that is easy one day, impossible the next.

Everyoen out there just needs to take all the variables into consideration before trying a shot on a game animal that might have seemed easy on it's 3D foam cousin a month earlier.
Maybe a decent rule of thumb would be, take whatever range you are comfortable with on the range, and realistically knock 5 or 10 yards off that for effective hunting yardages.
But like I said........every once in a while that bedded buck laying out there at the very edge of your comfort zone is going to look a lot like the "bedded buck" 3D target you were shooting a few weeks ago, and it's up to you to decide if you can do it, and I am not going to tell you that you can't.