I can help a little. Muzzleloaders are good to 100 yards and if you spend a lot of time with your rifle and can use a scope where you are hunting you can probably go out to 200 yards but that is only for a few that can spend the time and are steady enough to make those shots. Personally I consider my .50 cal Omega a 120 yard max shooter with a 1.5-5 scope. Elk when hit with 300gr. or 348gr. bullets do not drop on the spot when I do it. I have seen hunting shows where they do but my experience does not prove that it happens often. Haven't shot a Moose but they are bigger and probably as tough as an Elk so I doubt they will drop every time even when hit well. I would not shoot big bears with a muzzleloader as the second shot is sometimes a little slow and big bears "shoot back". Maybe little black bears might be OK but big brown bears are too mean for me. Generally most muzzleloaders will shoot better with a powder charge in the 100 to 120 grain level and when you go up to 150 most start losing accuracy and the extra powder is really unnecessary. 90gr. of Black Mag'3 with a 300gr. bullet passes completely through the chest cavity of a fair sized Elk. Cleaning by the way can be made a lot easier by selecting the powder that requires less to clean. Black Mag'3 is one of those types that leaves very little residue in the barrel and what is left is not corrosive so cleaning is fairly easy. A couple of patches run through with some windex (the non-amonia kind) followed by a couple of dry patches and then a patch with some kind of anti-rust oil and you are done. After multiple shots you will have to clean the breechplug as well but it is pretty easy.