For a grizzly id be more worried about penetration over any other factor, Id go with a heavy jacketed round nose soft point in the 300 grain range or a partition, id imagine most folks in here are gonna tell ya to go with a 300 grain cast lead bullet. any of those would be my choices for the 44 mag.

Personally if i was gonna tote grizzly repellent in the form of a handgun i might have went with a super redhawk in 454 casull or a BFR in 45-70.