Sure your 300's & 338 with those bolders will do it through the shoulder, but it ain't happening on a regular basis with a 270 and 130 gr. bullet. So Larry if I had to deal with that situation with my weapon and 130 Ballistic tip I would be eating tag soup before I attempted to place my shot in the shoulder, in the hopes I may find paydirt! A neck or spine I wouldn't think twice.