Really depends on your load combination.
With my loads for deer which are on the higher charge side, I sight in at 100 yards. Usually an inch or so high and that will leave me at 0" at 150yd.

I'll still back up to pattern at both 75 & 50 to see where things are and fine tune from there.

You don't want a combo that is 0" at 150 and 5+" high at 50-75 yards.