The 222 Rem. is probably the most accurate factory produced cartridge ever made. Its inherently more accurate then the 223 Rem. which is extremely accurate in and of its self. The 223 Rem. has a little bigger case so it holds more powder. I have a Remington model 700 BDL in 223 Rem. that shoots 1/2 groups with factory Remington 50 gr. V-Max ammo. I've never owned a more accurate rifle !