I've trap 1000+ fox in my life and 1 shot with little old .22 short right in ear area at 10' puts them down for good. I've also whack a few yote with the .220 swift never really had problems like you guys are talking. I, also shot a few of them both with scatterguns chased by dogs and either missed or planted them. 12 ga 5 shot turkey loads. 35 yds or closer.
ORIGINAL: Shotgun Mike
While out lamping once we shot a fox with a .243 at about 60yds. It ran on and we chased it and managed to hit it with the truck. We were 100% certain it was dead but when we reached the farm it was breathing again! A lump of wood finished the whole affair.