CVA Breechplug & Nipple Grease has anti-heat properties similar to the 2400* nickel/nuclear stuff. Put it on all threads... screw it in - take it out - re-lather.. then hand-tighten. The purpose of that is to ensure enough grease is on both bore threads & plug threads when using hot, magnum loads of 777. If magnum loads of 777 is what you use, then while at the range, loosen - then hand-tighten every 10 shots.

Using any other powder like Pyrodex, Goex?... put it on the threads & forget about it until you're done shooting. Then immediately after your last shot... while the barrel is still toasty-warm, loosen the plug two complete turns until you get the rifle home.