I would choose the 7mm-08 and use Barnes TSX bullets exclusively. I use the 140 gr. now for deer but the new 120 gr. will be my choice this year. Use the 140 for Elk or Caribou and you'll get great performance up to 200 yds. Much nicer to shoot the 7mm-08 also, it's light and easy to point and you can shoot it all day long at the range.