All things being equal, shot placement is the most critical regardless of what you are shooting.
The top end of the heart is what I am shooting for or else head shots if they are closer.

With hollowpoints, more rapid expansion is usually the result (Depending on the manufacturer) which can prevent them from exiting but also capable of delivering high energy impacts. However, I've also had dozens of hollowpoints that have exited deer.

The two hole theory is fine unless you hit them higher up. The chest cavity can hold a large amount of blood until you start seeing a trail and deer can do quite a bit of running around until that happens.

My .02