My 7mmstw's produce muzzle velocities of 3500fps with the 140gr ballistic tip and yet on a 25 yard shot,the bullet exited a deer that weighed in excess of 300lbs live weight.In fact,I have taken several deer with this cartridge where the impact velocity was still higher than the muzzle velocity of the 7mmremmag.
As far as moose are concerned,I have taken two mature bulls(1000lbs and 1200lbs) and eight elk with the 180gr ballistic tip out of my 300ultramags with very good results.I have never used the 165gr ballistic tip on large game.