A lot of it depends on the head, how large it is, the style and weight, and the specific brand. I can go from Muzzy 3 blade 100 grn to the 4 blade 100 grn with no noticeable change in accuracy for flight. As for preformance on game, I doubt their is going to be much differnce thier as well, provided you put the arrow in the proper place.

TAKE YOUR KIDS HUNTING AND YOU WON'T BE HUNTING FOR YOUR KIDS