generally I choose a load with the highest velocity with the lowest pressure but not always, lately with my 30-06 loads Ive been lookin at it from another way, lighter powder charges with good performance. Since hodgdon raised the price of their powder, last week I could get a pound of H4895 for $16.95 a pound, this week its $20.95 a pound. And those of you who pay regular retail prices you will notice the same 4 dollar increase if you payed 20 to 21 dollars a pound expect to pay 24 to 25 dollars a pound now.