well sence you have a deer round in case you leave the state i would go with a 22-250. work great on chucks and will cost a lot less then the 243 shells and the 243 would rip a yote up pretty bad. also you could get a 223 which is about the cheapest to shoot and will perform simular to the 22-250 with less fur damage.

or if you want to try something new look at the 204 ruger. i was shooting one about a month ago and it was really neat. it would make a decent long range caliber 3-500 yards because you can see your bullets hit through the scope so it makes for easy adjusments