I haven't had them both at the same time, but I have had both at one time or another. As far as I'm concerned, the VERY small advantage the Weatherby mag has over the .25-06 certainly isn't worth the high price of the ammo and the gun (of course the bargain bin vanguard is pretty cheap), but the ammo is a little too rich for the small advantage it gave, as far as I'm concerned...I didn't reload at that time either.

If you're wanting a weatherby and like the .257Wby. Mag, don't mind a limited selection of ammo, and don't mind the high ammo cost-reloading brings it down a lot and broadens your bullet type options-it's a great round and a great rifle...I'd just rather have two Rugers in .25-06 and .22-250 than one weatherby (which is the trade I made when I got rid of my Accumark).