I agree with most of you. You must be proficient at the longer ranges. The max effective range should be where your energy is around 1000 ftlbs. I believe with a 180 gr '06 average load, that may be around the 350 yd mark. Don't have a ballistic chart in front of me however so don't quote me.
Roger, I have a question for you. What is your scope sighted in for at 100 yds.? I figure if you were using 180 gr bullets you must be about 3" high at 100 yds. Or else you just got real lucky. I'm curious.
Cause I shot a mulie this past year at 438 yds with my 270 which shoots just slightly flatter than an '06 (130 gr Nosler @ 3000 fps) and my hold over was 3 feet with a sightin dead on at 100 yds. (I was using a Burris Ballistic Plex reticle scope).
My friend heart shot an antelope at 350 yds holding the horiz. crosshair on the back. He was using 180 gr handloads wighted in at 2 1/2" high at 100 yds.