Most if not all that buy the Weatherby brand are hung up on the name. I have a friend that spent a lot of $ on an Accumark topped with Swarovski glass. Is it a good setup? I suppose, but when I hold the rifle I don't get the impression that it's worth what it cost. May be just me. I'm sure you can get equal or better shooters for much less money with equal or better fit and finish. I would get a Sako over a Weatherby in that price range, personally, and would also have to look at Kimber.
The Vanguard has received a lot of bad word of mouth apparently from years past. Also, Weatherby made what I think to be is a bad decision in pulling that line out of all other shops and only selling thru WalMart. Some of my local shops were even surprised when I went in and asked about the Vanguard stating it was discontinued only to find out that it's just sold at WalMart. Most if not all also know that it's not made by Weatherby themselves so they immediately are turned off, without giving it a chance or bothering to research. Howa is now making the Vanguard series, as far as I know, and seem to be doing a decent job of it too. Don't know who made it way back when but it has left people with a bad impression of Vanguard's so they are still mostly ignored nowadays.
Talk of yesteryear affects a lot. To most, for example, if it isn't a Remington or Winchester it's not a rifle. When I first started researching and asked questions on the Tikka's I got all sorts of crap answers but no real reasons as to why they wouldn't be a good rifle. Same with Savage, except recently they seem to be turning it around. The old school hunters that are friends of mine though won't look twice at Savage, harkening back to the old days when apparently they built crap. Too bad for them as now they have good products.
Just my opinions and observations, do with them what you will.

By the way, it's "comparison". ;-)