If you're shooting off your knuckle, like real old-time archery, then it does make a difference. A right handed shooter would shoot left wing because the helical would take the leading end of the bottom hen feather away from his knuckle. That way he wouldn't get feather cuts. That's where the right handed/left wing, left handed/right wing rule came from. It's very, very old and mostly outdated.

Nowadays, shooting from elevated rests, or even off the shelf, it doesn't make any difference. Left wing fletched arrows will shoot to the same point of impact right wing arrows will.