RE: 45 or 50 cal
The T/C Omega .50 and the Knight Disc Elite .50 are the two best pure muzzleloaders going right now. The T/C Encore is great also if you prefer a gun that you can switch barrels on. By all means, I would get the .50 in whatever you buy. There's way more in the choice of projectiles for the .50 and most people seem to be able to achieve good accuracy out of a .50 with a little less trial and error than with a .45 ML. Good luck!