The Q2 is a great bow. All Mathews grips are aproblem in my view, though the new ones are better. Like you, I tried all kinds of thing like marking my hand for consistent placement and couldn't get comfortable.
Shrewd precision is the cure for me. I tried Loesch, but had some of the same problems.
http://www.shrewd-one.com/
Not everyone seems to have these problems. But here is a shooter shooting off the riser with something:
http://www.photoreflect.com/scripts/...um=0&adjust=-1