I have used the Sierra Boat Tail 100 gr Fed Premiums on a few deer. All I will say is I wont be using them again...bullets are very frangible. I wont carry the 243 back out with anything less than a Nosler and its probably not gonna see deer duty again. Too many variables with that round for me.....lthough most report good success with the 100 gr Noslers...so I may load some of those and give it another crack.