I am no expert, do not have alot of practical knowledge, but have read some since i too am looking for a new rifle.
Most of the friends i hunt with use a 270. They like the fact that it is not too loud. Does not kick too much and gets the job done. But i have also read an article in outdoor life that the 270 caliber has accuracy problems.
I have a 30-06 that i can not shoot unless i am wearing ear plugs. I flinch every time.
The 7mm bullets are supposed to be accurate ( according to a speer manual). I am wondering if the 7mm-08 might have the best all round qualities for deer sized game.