Just a note on meat loss:
I butcher deer among other critters and everyone always tells me they want all the meat that I can salvage. If you hit a deer in the shoulder, that shoulder is at least 80% shot in most cases. It is not just the wound channel itself that destroys meat, but the hydrostatic energy dissipated through the animinal as the bullet passes. It is like dropping a rock in a lake, the water ripples, same for the muscle in an animinal (same effect animinals and ourselves are mostly composed of water), the first few "rings" of the ripple destroy the meat. For greatest meat yeild you need to hit the deer in the head (not the neck, there goes meat!) or directly in the vitals. Too many deer come in with poor shot placement. If hit in the vitals the 300 Win mag will destroy no more, no less meat than any other caliber, my personal observation.