velocity?? the 243 is doing like 50fps more out of the muzzle from the chart im looking at...150gr 3006 and 100 gr 243 bullets.....but energy isnt even comparable....the 06 has almost 1000lbs more out of the muzzle.......sure the 243 works....and they both kill when put into the boiler room.....but the 30cal has alot more energy and mass....and will open up bigger and punch bigger better wound channels....but the 243 has killed mannnnnnnnny deer...it works.....but the 30cals will do the trick better id have to say.....