It really depends on how long of a shot you'll be taking. If your shots will be in the neighborhood of 100yds, a revolver will do just fine in the calibers you mentioned. But for longer shots, a T/C or the Striker from Savage in a rifle caliber will be the better choice. When I first got into pistol hunting, I bought a Ruger in 44mag because the place I hunted never offered a shot over 100yds. But, I've since gone to another spot where shots can be in excess of 200yds, so I went with the T/C's. I've still got a T/C Contender in 44mag for the shorter shots, but also have an Encore in 308 for when I need to stretch it out a little. Like I said, it all depends on the terrain you'll be hunting.