I can proudly say yes. I have a .45 cal T/C Encore. I have a .25ACP breach plug from Precision Rifle, and a Weaver Grandslam 3.5-10 50MM scope. I'm shooting Precision Rifle dead center 175 Gr bullets. Backed with 130 Grains of powder. Once I found this load, I have not shot over 3'' groups at 250 yards. The best part is I have the gun sighted in at 200 yards. It hits 2'' high at 150yards, and 3'' low at 250. Precision Rifle are the guys to get in touch with for long range shooting. PrBullet.com

Note: Dead Center bullets are solid lead. Although I have not had a problem with them on deer size game, I would not recommend them for much more. I have shot deer at 40 yards with these bullets, small deer, and the bullets did not come out. At 100 yards the bullet performance was flawless, however I would not shot bigger game at close yardages.