Can I "know" the drops for each load at distance and be able to adjust the scope accordingly?
Well, you can use ballistics tables/calculations to get this information. BUT be advised that the data you get this way MAY OR MAY NOT conform to what an individual rifle actually does when fired with a given load. The ONLY way you can know FOR SURE what your rifle actually does WITH EACH DIFFERENT LOAD, is by shooting it with that load on a known-distance range, all the way out to the longest range at which you are willing to shoot at something.
Check out this site: It can do the caluculations for any load, as long as you know the ballistic coefficient of the bullt, the MV, and the zero range.....
http://www.biggameinfo.com/BalCalc.aspx
Good luck!