No real difference in speed between the average single cam and the average hybrid design...at least none that I have noticed. The advantage to the hybrid design is that they normally provide straight and level nock travel thus making the bow easier to tune and subsequently more accurate with exposed blade broadheads. The string and two cable (or two strings and single cable if you like) setup on the hybrids is less likely to stretch as much as the long strings found on conventional solo cam designs. This helps the bow continue to remain more accurate over the long term with as little additional tuning as possible.

As for actual shooting characteristics...that is a toss up. I have found that the bow's physical characteristics during the shot (how easy it draws, recoil/vibration, noise, etc...) are all more dependent on a variety of additional issues like limb angle, preload on the limbs, riser design, etc... rather than just the cam style. Each has their benefits but it is up to the individual shooter to determine what feels best for them. Considering the level of sophistication in bow design and materials I think you would be hard pressed to find a mid to high priced model that is unpleasant to shoot.