The original comparison was a 40mm scope and a 50mm scope.The 40mm scope can be mounted in medium rings while the 50mm requires high rings with most rifles.The difference can make a difference obtaining proper cheek position on the stock.As stated before,4.5x14 is far more power than required for big game hunting and can be a hindrance at very close range.I have shot big game myself out to well over 400 yards with a 3x9 scope and had no problems doing so. I would look at the 3x9x40 ziess conquest as it offers enough power ,has 4" of eye relief at all powers and costs the same as the leupold 3.5x10x40.