I was just on winchesters web site they have a 45 long colt load which is a 225 gr. Super-X Silvertip Hollow Point pushing 920 fps from a 5.5 inch barrel I think that would be more then adequate for deer. A friend of mine back home in missouri uses winchesters 44 special loading with a 200 gr silvertip hollow point for handgun hunting deer according to the webpage this load pushes 900 fps from a 6.5 inch barrel. My friends gun is rugers vaquero 44 mag chamber with a 4 5/8" barrel. He uses 44 specials because he cant shoot magnums consistantly due to the heavy recoil, but he has killed quite a few deer with it rarely needing more then one shot.