Just about everyone here has raised all the points to consider between the two cartridges. Of course, I'm biased, and I stick by the .30-06. While the velocities aren't that much greater than the .308, I'd rather go higher than lower. In addition, the .30-06 can handle heavier bullets and even approach magnum performance with the right bullet/powder combination. That versatility is what I look for in a do-it-all rifle.