Yep, took a buddy of mine out yesterday to site in his 30-06
Last year he was shooting some 125 gr Ballistic tips for antelope and was dead on with them.
At the range he had some 165s 'just to shoot' and it was a good thing he just wanted to shoot them up because he sure couldn't hit anything!!

Funny thing is, he had some Rem. green box 150s that he proceeded to shoot into one tiny little hole before we left.

Go Figure.