Almost any caliber will kill your wife. Let me ask you a few questions to boil the list down.

1. What range do you think you'd take the shot? Will you only shoot across the kitchen or can you hit from really long range like from the bedroom all the way to the living room?
2. Are there any crossings that she might be funneled through? In the mornings you may have a quick open shower stall shot but I've always had better luck at the vanity they hang out there much longer. That spot between the couch and the coffee table would be great for an evening stand. It's a real pinch point.
3. Have you done any scouting? I'd set up between the food and the bedding area as usual. But some guys are finding more sign near the telephone.
4. Have you got a good set of optics? In this case ground shrinkage is a good thing.
5. Do you plan on baiting? Every year I hear guys using fried chicken or nacho cheese Doritos but more and more guys have luck with Reese's candy over any other brand.
6. Decoys are clumsy but effective. I have an old poster of Pierce Brosnan as 007 you can borrow. It's been attacked frequently but has held together.
7. Calls have mixed results. I'd try playing any song on the Hi-Fi by Bon Jovi in the northern latitudes while Brooks and Dunn works better in the south.
8. Rut dates are especially difficult to pin down. Generally any time within a week of your anniversary can be productive.
9. Scents are great. Code Blue has a new scent called "eau de Mercedes" that draws women like flies.
10. Don't worry about wind currents unless you created your own after a Mexican dinner if you know what I mean. But if you must fart (and you're good at snap shooting) like the commercial says "forget the wind just hunt".
11. Before you bring her down I'd have the price hammered out with your taxidermist first about this? Sometimes they have a special 2 for 1 for buddy deals. Some guys like the knealing pose but that's extra. At least it doubles as a place to put the TV remote but to each their own.