I agree, the Easton Tuning guide is a great place to find some good info.

I'm sure every bow is different, but I'm guessing you'll find much better arrow flight if you set your nock almost right at 90 degrees with the biscuit.

As far as center shot, I'd also guess that it will likely end up a little further from your riser. Shoot at that vertical line as Bowshopper mentioned and don't worry about moving your pins at this point. As you shoot from futher back, your arrows should be impacting in the same relation to that vertical line. If they move further left/right as you move back adjust your rest accordingly. Once you've got them all hitting the same vertical line, then you can adjust your sight left/right & then you should be ready to set the elevation of your pins.