When I owned a 06 all I used was Partitions 165 gr for deer and 180 for the bigger stuff. However I know 4 guys who use the 06 for deer hunting 2 use 150 gr Hornady SPBT's and the other 2 use 165gr Nosler Ballistic Tips. Anywhere between 150-165gr should be perfect (180's I think are a bit stiff for the likes of deer but will work), just pick the right bullet for your situation and the one the guns likes to fling!