I think you are overthinking this.
I think you are right I've been driving my self crazy with this LOL last night I hardly slept thinkin about it. 2700 fps is kinda the magic velocity to me since the factory ammo I shot forever was remington 165 grain BTSP's they had, well according to the packaging muzzle veloc. of 2700 fps but for factory ammo at 100 yards they shot awesome the groups looked like one ragged hole. just at 17 dollars for 20 shots was getting rediculous especially as much as I want to shoot reloading was the only answer. I suppose I am trying base my reloads on the accuracy I experienced with those, and yes I am thinking about it tomuch. what I am gonna do just stick with th 45 grains play with the bullet seating depth see what I get, if nothing I will try something else. My biggest problem I think I am doing is I know in reloading asfar as accuracy is concerned there is alot of trial and error to be worked out before you have a good load, I am trying to work out the problems in my head and its not working.