I use Rel. 22 with the Nosler 200 gr BT for deer and 225 gr Nosler Part. for elk. I killed an Elk last year at about 100 yd. with the 225 Part. never moved out of its tracks. I killed a whitetail buck at 419 yd on the laser range finder with 200 BT never even finched just dropped and slid down the hill without even a kick. The loads were right out of the Nosler Manual. I can remember the exact load would have to look them up in my load book. Just remember to use Mag Primer in the 338 UM. I use nothing but Fed 215 in my mag rifles.