Relative to amount of charge for Elk. Two years ago I shot a 600 lb. Cow Elk from about 80 yards with a short barrel T/C .50cal. using 80 grains of clean shot and a 348gr. powerbelt bullet. The bullet turned sideways and may have actually keyholed as the clean shot was probably not powerful enough to upset the Powerbelt properly (CVA said the pressure rise on that powder was too slow). The bullet went through the left front shoulder through the center of the heart and stuck in the rib/shoulder area on the far side. The plastic tip was still in the bullet and the side was somewhat flattened. I now use an Omega and about 80 grains of Pyrodex or 777 with the same bullet and am not concerned that I have enough power. If you shoot well over 100 yards that might change things but at 100 yards or less 80 grains of powder with a 348gr bullet is plenty. I may change to 300gr. Hornady SST and up the charge a little to closer to 100 grains depending on how the combination shoots. The Hornady bullet really looks cool and I have a lot of respect for the Hornady people.