I would consider proper nock to string fit to be a commonly overlooked or ignored tuning or troubleshooting consideration.
Absolutely! Especially with todays speed demons.
I carry a minimum of roughly 3 dozen nocks of various colors for my carbons in my bow case so I can replace one quick and easy anytime during practice. It also gives me satisfaction to pull one out when I see someone bust a nock at the range and fix them up in a hurry.
It isn't as quick and easy when I shoot my aluminums but I still check them and replace them often.